Try going to start,run, and typing %temp% and hit enter. Clear those files... then go to the prefetch folder in Windows and see if it shows there. Then try this utility to clean all other folders. http://www.atribune.org/content/view/25/2/
Do a search for the folder in question and delete it.. If you still have problem after that post a HJT log for the security guys to look at.
The prefetch folder is supposed to make things start faster, but there is lots of debate as to if it actually does.. just as there is lots of debate as to empying the contents speeds up your pc. But it is safe to remove all the contents.
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