Is drive D a partition or is it a physical drive? If it is a physical drive and if this is a desktop, open the side of the case and check that the hard drive cable plug is firmly pushed in - on both the hard drive end and the motherboard.
If you suspect this is caused by malware - a fake Nvidia Update, then, with the USB stick plugged in, do full scan with Windows 10 Windows Defender. Then download Malwarebytes and do a scan. Then google for 'online scan', there will be several big name antivirus companies that show up, like Kaspersky, ESET, Trendmicro. Do a scan with one of those - it will take 15 mins or more.
If you suspect this is caused by malware - a fake Nvidia Update, then, with the USB stick plugged in, do full scan with Windows 10 Windows Defender. Then download Malwarebytes and do a scan. Then google for 'online scan', there will be several big name antivirus companies that show up, like Kaspersky, ESET, Trendmicro. Do a scan with one of those - it will take 15 mins or more.